EXOSC3(exosome component 3)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

9p11
基因染色体位置图

基因简述

基因简述

This gene encodes a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2012]

[中文简述(自动翻译):]  该基因编码的人类外来体的非催化组分，与起着众多RNA加工和退化活动角色3‘-5‘核糖核酸外切酶活性的复合物。该基因相关的假都在19号染色体和21的编码已被描述不同的亚型选择性剪接转录变异体中。 [由RefSeq的，2012年6月提供]

OMIM数据库中对EXOSC3基因的介绍     Wikipedia数据库中对EXOSC3基因的介绍

基因序列

基因序列

EXOSC3基因的碱基序列：[NCBI]

基因突变

基因突变

EXOSC3基因的碱基突变：           显示全部snp
rs7158       rs1059059       rs2274322       rs2281871       rs2296551       rs3208406       rs3761669       rs3761670       rs3789021       rs3827515       rs6476661       rs7029518       rs7039137       rs7042945       rs7847962       rs7861152       rs7868743       rs10973540       rs10973541       rs10973542       rs11420298       rs12002972       rs13294227       rs28369461       rs34753153       rs62640002       rs62640003       rs62640004       rs73649213       rs73649214       rs75756672       rs75826395       rs76964682       rs77041402       rs78363453       rs78390218       rs112035268      
rs112617599       rs112632776       rs112840537       rs112985168       rs113148476       rs113393314       rs113427983       rs113915464       rs113930100       rs114826945       rs114878910       rs114951310       rs115431773       rs115613862       rs116182504       rs116223769       rs117073203       rs117082934       rs117994530       rs138085418       rs138169215       rs138197600       rs138287071       rs138581086       rs139360012       rs139470852       rs139471659       rs139476262       rs139911906       rs140159471       rs140199968       rs140345562       rs141077639       rs141138948       rs141464856       rs141785095       rs142103242       rs142727320       rs143319153       rs143717362       rs144945605       rs144999041       rs145041725       rs145464176       rs145622193       rs145677716       rs147135294       rs147138174       rs147361668       rs147384411       rs147510873       rs147547132       rs147568068       rs147746819       rs148327904       rs148348866       rs148650086       rs148963507       rs149049356       rs149288698       rs149512504       rs149583035       rs149836327       rs150409666       rs150570229       rs180683505       rs181508905       rs181885995       rs182102358       rs182482824       rs182650669       rs183218944       rs183298591       rs183399179       rs183624321       rs185029364       rs185068713       rs185079062       rs185234870       rs185352572       rs185885745       rs187539887       rs187809800       rs188279249       rs188744146       rs189990241       rs191065591       rs191434395       rs191458589       rs191890161       rs192042969       rs192341568       rs192643385       rs192949782       rs199651233       rs199677116       rs199826705       rs199954489       rs200453185       rs200567248       rs201178873       rs201572296       rs201850790       rs201949026       rs202059195       rs368076549       rs368757759       rs368960548       rs369075932       rs369665310       rs370087266       rs370102047       rs371714629       rs371853233       rs371885660       rs371980686       rs372128042       rs372417711       rs373191549       rs373193552       rs373242406       rs373502396       rs373646014       rs373942170       rs374094769       rs374550999       rs374837436       rs375827861       rs376325566       rs376907861       rs377676582       rs387907196       rs527405670       rs527443245       rs528594042       rs528628316       rs530037792       rs530072674       rs530878018       rs530895640       rs530898813       rs532302411       rs532467237       rs532743922       rs533644778       rs534786669       rs534890103       rs535370583       rs535504227       rs536360468       rs536496587       rs536525994       rs537289113       rs537330212       rs537356375       rs537530479       rs537970390       rs538333341       rs538368141       rs538521590       rs538741249       rs541664197       rs542055423       rs542717089       rs542894858       rs543164025       rs543479413       rs543643932       rs543679048       rs543767697       rs545145675       rs545495474       rs545630638       rs546801535       rs546917405       rs547141617       rs547846783       rs548993202       rs549030188       rs549207852       rs550988823       rs551521305       rs551825536       rs552385358       rs552983791       rs553028102       rs553232437       rs554134988       rs554136949       rs554174087       rs554341775       rs555002499       rs555232386       rs555925582       rs556193388       rs556303288       rs557187129       rs557224299       rs557688440       rs557993345       rs558252904       rs558544933       rs558579097       rs558944939       rs559127155       rs559508508       rs561205536       rs561283125       rs561317388       rs562414869       rs562722636       rs563290543       rs563329272       rs563554343       rs564287785       rs564844297       rs565299299       rs565320740       rs565334207       rs565884761       rs565950496       rs566332754       rs566520412       rs566642894       rs566678720       rs567442831       rs567470252       rs567605961       rs567641975       rs567727126       rs567862597       rs568516772       rs568938664       rs568976462       rs569101280       rs569527884       rs569717812       rs570324264       rs570436113       rs570898670       rs571531964       rs571596234       rs572041344       rs572845857       rs573008856       rs573317999       rs573361407       rs573816850       rs574028432       rs574858245       rs575140512       rs575715001       rs575794407       rs575993793       rs577172717       rs577734171       rs577945531       rs730882145       rs745343798       rs745785017       rs745981409       rs746072600       rs746439813       rs746924619       rs747030782       rs747459915       rs747513459       rs747704846       rs747777759       rs747883936       rs748111732       rs748194453       rs748282500       rs748651701       rs748839685       rs748976233       rs749142446       rs749237338       rs749295866       rs749691951       rs750016815       rs750172761       rs750268758       rs750485929       rs750712880       rs751095415       rs751582737       rs751776878       rs751894457       rs752657393       rs752745392       rs752749069       rs752953027       rs753041344       rs753042657       rs753133011       rs753407051       rs753499063       rs753698044       rs753739586       rs753935327       rs754046728       rs754445527       rs754667929       rs754771911       rs754877763       rs754973221       rs755145404       rs755175121       rs755802507       rs756273465       rs756503706       rs756702077       rs756970445       rs757129344       rs757481488       rs757780996       rs757789978       rs758230758       rs758232407       rs758427169       rs758556568       rs758859987       rs758899003       rs759096213       rs759103564       rs759334071       rs759452295       rs759640219       rs759834028       rs760030050       rs760424055       rs760466382       rs760815181       rs761430695       rs762038657       rs762278752       rs762496779       rs763414837       rs763578838       rs763964643       rs764031129       rs764503826       rs764545296       rs764566949       rs764928491       rs764975416       rs765016508       rs765457042       rs765608479       rs765807865       rs766063373       rs766151287       rs766370104       rs766461372       rs766464639       rs766811932       rs767003713       rs767203592       rs767393720       rs767522178       rs767879780       rs767942736       rs768414644       rs768439296       rs768507877       rs768917662       rs768949188       rs769374744       rs769410295       rs769415473       rs769547087       rs769554336       rs769746459       rs770068408       rs770262381       rs770631226       rs770922813       rs771261237       rs771263198       rs771457344       rs771577074       rs771687142       rs772252048       rs772480946       rs772977624       rs773074912       rs773161484       rs773265763       rs773436764       rs773573166       rs773767698       rs774032069       rs774069700       rs774107001       rs774500797       rs774698785       rs774976928       rs775189351       rs775818894       rs776118147       rs776409249       rs776611730       rs776681485       rs777069729       rs777230686       rs777240296       rs777626686       rs777709692       rs777930611       rs778368932       rs778372165       rs778400947       rs778480656       rs778568478       rs778675403       rs779053512       rs779614399       rs779619010       rs780093244       rs780279833       rs780590438       rs780777501       rs780863201       rs780933822       rs781526423       rs781685540      

基因表达

基因表达

EXOSC3基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GTGAGCCAGCTTCTTTGTC
59
TCTGGAGCTAATAGCCTGC
59
GTGAGCCAGCTTCTTTGTC
59
TGGAGCTAATAGCCTGCAC
60
GTGAGCCAGCTTCTTTGTC
59
TGAGATCTCCAACCTGCAC
59
CCAAATGTGCAGGTTGGAG
59
AATACAGACCATCTCTGGTTCC
60
CGTTTGGAGTCTCAGAGGG
60
ACTGGAACATACTGTTCTAGGAG
59
AAATGTGCAGGCTATTAGCT
58
TTCCAAATACTATCTCCAGTGG
57
CAGAAGCGGTATGTTCCAG
58
CAAAGAAGCTGGCTCACTC
59
CAGAAGCGGTATGTTCCAG
58
AAGACAAAGAAGCTGGCTC
58
CAGAAGCGGTATGTTCCAG
58
CAAAGAAGCTGGCTCACTC
59
CAGCTTCTTTGTCTTACTTGTC
58
CATAGATGAGATCTCCAACCTG
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

EXOSC3基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

EXOSC3基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000175
Q9NQT5(UniProtKB)
NAS
GO:0000176
Q9NQT5(UniProtKB)
IDA
GO:0000177
Q9NQT5(UniProtKB)
IDA
GO:0000178
Q9NQT5(UniProtKB)
IDA
GO:0000467
Q9NQT5(UniProtKB)
IBA
GO:0003723
Q9NQT5(UniProtKB)
IBA
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005515
Q9NQT5(UniProtKB)
IPI
GO:0005634
Q9NQT5(UniProtKB)
IDA
GO:0005654
Q9NQT5(UniProtKB)
TAS
GO:0005654
Q9NQT5(UniProtKB)
TAS
GO:0005730
Q9NQT5(UniProtKB)
IDA
GO:0005737
Q9NQT5(UniProtKB)
IDA
GO:0005829
Q9NQT5(UniProtKB)
TAS
GO:0005829
Q9NQT5(UniProtKB)
TAS
GO:0005829
Q9NQT5(UniProtKB)
TAS
GO:0005829
Q9NQT5(UniProtKB)
TAS
GO:0006364
Q9NQT5(UniProtKB)
IDA
GO:0006364
Q9NQT5(UniProtKB)
TAS
GO:0034427
Q9NQT5(UniProtKB)
IBA
GO:0034475
Q9NQT5(UniProtKB)
IBA
GO:0035327
Q9NQT5(UniProtKB)
IMP
GO:0043488
Q9NQT5(UniProtKB)
TAS
GO:0043488
Q9NQT5(UniProtKB)
TAS
GO:0043488
Q9NQT5(UniProtKB)
TAS
GO:0043928
Q9NQT5(UniProtKB)
IMP
GO:0043928
Q9NQT5(UniProtKB)
TAS
GO:0045006
Q9NQT5(UniProtKB)
IDA
GO:0045190
Q9NQT5(UniProtKB)
ISS
GO:0045830
Q9NQT5(UniProtKB)
IEA
GO:0071034
Q9NQT5(UniProtKB)
IMP
GO:0071035
Q9NQT5(UniProtKB)
IBA
GO:0071038
Q9NQT5(UniProtKB)
IBA
GO:0071049
Q9NQT5(UniProtKB)
IBA
GO:0071051
Q9NQT5(UniProtKB)
IBA
GO:0004532
Q9NQT5(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控EXOSC3基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Pontocerebellar Hypoplasia Type 1 0.241628651 6 3 BeFree_CTD_human_ORPHANET
PONTOCEREBELLAR HYPOPLASIA, TYPE 1B 0.24 1 8 CLINVAR_UNIPROT
Congenital pontocerebellar hypoplasia 0.000814326 3 2 BeFree
Pontoneocerebellar hypoplasia 0.000814326 3 2 BeFree
Epilepsy 0.000271442 1 0 BeFree
Glioblastoma 0.000271442 1 0 BeFree
Glomerulonephritis 0.000271442 1 0 BeFree
HIV Infections 0.000271442 1 0 BeFree
Meningioma 0.000271442 1 0 BeFree
Monosomy 0.000271442 1 0 BeFree
Muscle hypotonia 0.000271442 1 1 BeFree
Mycoses 0.000271442 1 0 BeFree
Paracoccidioidomycosis 0.000271442 1 0 BeFree
Trisomy 0.000271442 1 0 BeFree
Motor Neuron Disease 0.000271442 1 0 BeFree
Cerebellar Hypoplasia 0.000271442 1 0 BeFree
Complicated hereditary spastic paraplegia 0.000271442 1 0 BeFree
Cerebellar atrophy 0.000271442 1 0 BeFree

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