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Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. [provided by RefSeq, May 2009]
[中文简述(自动翻译):]  弹性蛋白酶形成水解许多蛋白质??除了弹性丝氨酸蛋白酶亚科。人类有其编码结构上类似的蛋白质的弹性蛋白酶1,2,2A,2B,3A,和3B 6弹性蛋白酶的基因。像大多数人弹性蛋白酶的蛋白酶,弹性蛋白酶2A是从胰脏作为酶原分泌。在其他物种,弹性蛋白酶2A已经显示出优先地切割后亮氨酸,甲硫氨酸和苯丙氨酸残基的蛋白。 [由RefSeq的,2009年5月提供]
CELA2A基因(以及对应的蛋白质)的细胞分布位置:
CELA2A基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Hypertensive disease | 0.12 | 1 | 0 | CTD_human |
Erectile dysfunction | 0.002367032 | 1 | 1 | GAD |
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