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This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]
[中文简述(自动翻译):]  该基因编码抗微生物肽家族中的一员,其特征在于含有凯萨林结构域和结构变量阳离子抗微生物肽,其是通过从C末端胞外蛋白水解产生的高度保守的N-末端信号肽。除了它的抗菌,抗真菌和抗病毒活性,在细胞趋化,免疫介体诱导,和炎症反应调节所编码的蛋白质的功能。 [由RefSeq的,2014年9月提供]
CAMP基因(以及对应的蛋白质)的细胞分布位置:
CAMP基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Sepsis | 0.081085767 | 5 | 0 | BeFree_RGD |
Meningitis, Pneumococcal | 0.08 | 1 | 0 | RGD |
Infection | 0.010897401 | 4 | 0 | LHGDN |
Tuberculosis | 0.006534468 | 6 | 0 | BeFree_LHGDN |
Atherosclerosis | 0.006263026 | 4 | 0 | BeFree_LHGDN |
Asthma | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Bacterial Infections | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Lung diseases | 0.002995792 | 1 | 0 | BeFree_LHGDN |
Chronic Obstructive Airway Disease | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Psoriasis | 0.002985861 | 11 | 0 | BeFree |
Cellulitis | 0.00272435 | 1 | 0 | LHGDN |
Cystic Fibrosis | 0.00272435 | 1 | 0 | LHGDN |
Down Syndrome | 0.00272435 | 1 | 0 | LHGDN |
Inflammation | 0.00272435 | 1 | 0 | LHGDN |
Leukemia, Myelocytic, Acute | 0.00272435 | 1 | 0 | LHGDN |
Lung Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
Neutropenia | 0.00272435 | 1 | 0 | LHGDN |
Mammary Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
Dermatitis, Atopic | 0.002442977 | 9 | 0 | BeFree |
Eczema | 0.002442977 | 9 | 0 | BeFree |
Gingival Diseases | 0.001628651 | 6 | 0 | BeFree |
Periodontal Diseases | 0.001628651 | 6 | 0 | BeFree |
Arteriosclerosis | 0.000814326 | 3 | 0 | BeFree |
HIV Infections | 0.000814326 | 3 | 0 | BeFree |
Septicemia | 0.000814326 | 3 | 0 | BeFree |
Carcinogenesis | 0.000814326 | 3 | 0 | BeFree |
Malignant neoplasm of breast | 0.000542884 | 2 | 0 | BeFree |
Malignant tumor of colon | 0.000542884 | 2 | 0 | BeFree |
Cholesteatoma | 0.000542884 | 2 | 0 | BeFree |
Craniosynostosis | 0.000542884 | 2 | 0 | BeFree |
Dermatitis | 0.000542884 | 2 | 0 | BeFree |
leukemia | 0.000542884 | 2 | 0 | BeFree |
Lupus Erythematosus, Systemic | 0.000542884 | 2 | 0 | BeFree |
Neoplasm Metastasis | 0.000542884 | 2 | 0 | BeFree |
Ovarian Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Dermatologic disorders | 0.000542884 | 2 | 0 | BeFree |
Meningitis, Bacterial | 0.000542884 | 2 | 0 | BeFree |
Chronic sinusitis | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of lung | 0.000542884 | 2 | 0 | BeFree |
Psoriasis vulgaris | 0.000542884 | 2 | 0 | BeFree |
Chronic Periodontitis | 0.000542884 | 2 | 0 | BeFree |
Congenital neutropenia | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of prostate | 0.000542884 | 2 | 0 | BeFree |
Prostate carcinoma | 0.000542884 | 2 | 0 | BeFree |
Breast Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Colon Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of ovary | 0.000542884 | 2 | 0 | BeFree |
Cancer Cell Growth | 0.000542884 | 2 | 0 | BeFree |
Aggressive periodontitis, generalized | 0.000542884 | 2 | 0 | BeFree |
Severe congenital neutropenia | 0.000542884 | 2 | 0 | BeFree |
Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Autoimmune Diseases | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of urinary bladder | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of thyroid | 0.000271442 | 1 | 0 | BeFree |
Cardiomyopathy, Dilated | 0.000271442 | 1 | 0 | BeFree |
Cystitis | 0.000271442 | 1 | 0 | BeFree |
Dental caries | 0.000271442 | 1 | 0 | BeFree |
Shigella Infections | 0.000271442 | 1 | 0 | BeFree |
Gaucher Disease | 0.000271442 | 1 | 0 | BeFree |
Glioma | 0.000271442 | 1 | 0 | BeFree |
Graves Disease | 0.000271442 | 1 | 0 | BeFree |
Herpesviridae Infections | 0.000271442 | 1 | 0 | BeFree |
Immune System Diseases | 0.000271442 | 1 | 0 | BeFree |
Keloid | 0.000271442 | 1 | 0 | BeFree |
Acute lymphocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
Myeloid Leukemia | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of stomach | 0.000271442 | 1 | 0 | BeFree |
Meningitis | 0.000271442 | 1 | 0 | BeFree |
Mycobacterium Infections | 0.000271442 | 1 | 0 | BeFree |
Pustulosis of Palms and Soles | 0.000271442 | 1 | 0 | BeFree |
Papillon-Lefevre Disease | 0.000271442 | 1 | 0 | BeFree |
Periodontitis | 0.000271442 | 1 | 0 | BeFree |
Prostatic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Rosacea | 0.000271442 | 1 | 0 | BeFree |
Skin lesion | 0.000271442 | 1 | 0 | BeFree |
Tuberculosis, Pulmonary | 0.000271442 | 1 | 0 | BeFree |
Vitamin D Deficiency | 0.000271442 | 1 | 0 | BeFree |
Severe Combined Immunodeficiency | 0.000271442 | 1 | 0 | BeFree |
Tumor Progression | 0.000271442 | 1 | 0 | BeFree |
Diabetic Foot | 0.000271442 | 1 | 0 | BeFree |
Cyclic neutropenia | 0.000271442 | 1 | 0 | BeFree |
Childhood asthma | 0.000271442 | 1 | 0 | BeFree |
Solid tumour | 0.000271442 | 1 | 0 | BeFree |
stage, prostate cancer | 0.000271442 | 1 | 0 | BeFree |
Caries (morphologic abnormality) | 0.000271442 | 1 | 0 | BeFree |
Impaired cognition | 0.000271442 | 1 | 0 | BeFree |
Eosinophilic esophagitis | 0.000271442 | 1 | 0 | BeFree |
Immune thrombocytopenic purpura | 0.000271442 | 1 | 0 | BeFree |
Subgingival plaque | 0.000271442 | 1 | 0 | BeFree |
Thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
Stomach Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of bladder | 0.000271442 | 1 | 0 | BeFree |
Chronic neutropenia | 0.000271442 | 1 | 0 | BeFree |
Helicobacter pylori infection | 0.000271442 | 1 | 0 | BeFree |
lung cavity | 0.000271442 | 1 | 0 | BeFree |
ovarian neoplasm | 0.000271442 | 1 | 0 | BeFree |
Eczema Herpeticum | 0.000271442 | 1 | 0 | BeFree |
Sarcoma | 0.000271442 | 1 | 0 | BeFree |
Pancreatic Ductal Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Diabetic foot ulcer | 0.000271442 | 1 | 0 | BeFree |
Precursor Cell Lymphoblastic Leukemia Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Promyelocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
Albright's hereditary osteodystrophy | 0.000271442 | 1 | 0 | BeFree |
Limb ischemia | 0.000271442 | 1 | 0 | BeFree |
Pseudohypoparathyroidism, Type Ia | 0.000271442 | 1 | 0 | BeFree |
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