Lynch(H T),Brodkey(F D),Lynch(P),Lynch(J),Maloney(K),Rankin(L),Kraft(C),Swartz(M),Westercamp(T),Guirgis(H A)
状态:
发布时间1976-09-25
, 更新时间 2016-10-17
期刊:
JAMA
摘要:
An intensive study of the family history of cancer in 4,515 patients screened consecutively by a multiphasic mobile cancer detection unit showed, after age correction, that cancer had developed in 8.9% of the probands when there was one cancer in a single first-degree relative, 16.2% had cancer with two family members affected, and 27.4% had cancer when three or more family members had been affected. This constituted a significant correlation between family and personal histories of cancer in these patients. Extrapolation to the United States population with cancer-control implications are given.