| GeneLibs

题目:: Genetic markers and cancer epidemiology.
作者:: Petrakis(N L),King(M C)
状态:: 发布时间1977-06-11 , 更新时间 2010-11-18
期刊:: Cancer
摘要:: The study of potential associations between genetic markers and various cancers has a long history in cancer epidemiology. Such investigations are subject to serious problems of statistical significance and the choice of appropriate control populations. A promising future for the use of human population genetics in cancer epidemiology may be in the investigation of genetic markers (such as the HL-A complex) which code for proteins of potential immunological or physiological importance in susceptibility or resistance to cancer. The cerumen gentic marker has played a central part in a hypothesis formulated in our laboratory for the etiology of breast cancer. A second new development in this field is likely to be the investigation of genetic markers in families with high incidence of cancer. Such families permit the simultaneous study of genetic hypotheses of cancer inheritance and the association of marker genotypes with cancer through segregation and linkage analysis.
语言:: eng
DOI:

文献库文献相关信息