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题目:: Y chromosome abnormality in human stomach and lung cancer.
作者:: Wada(M),Yokota(J),Mizoguchi(H),Terada(M),Sugimura(T)
状态:: 发布时间1987-11-06 , 更新时间 2006-11-15
期刊:: Jpn J Cancer Res
摘要:: Sex chromosome abnormalities in human stomach and lung cancers from 33 male patients were examined by Southern blot hybridization with pDP34 DNA probe, which recognizes X and Y chromosome-linked restriction fragment length polymorphisms (RFLPs). Contrary to the recent cytogenetic observations showing high incidence of loss of the Y chromosome in solid tumors, loss of the Y chromosome was observed in only 3 of 21 stomach cancers and 2 of 12 lung cancers. Gain of the Y chromosome was found in one of 12 lung cancers, but not in any of the stomach cancers. No X chromosome abnormality was found in any of these 33 stomach cancers and lung cancers.
语言:: eng
DOI:

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