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题目:: Identification of Gastric Cancer Biomarkers Using 1H Nuclear Magnetic Resonance Spectrometry.
作者:: Ramachandran(Gokula Krishnan),Yong(Wei Peng),Yeow(Chen Hua)
状态:: 发布时间2016-09-10 , 更新时间 2016-09-29
期刊:: PLoS One
摘要:: Existing gastric cancer diagnosing methods were invasive, hence, a reliable non-invasive gastric cancer diagnosing method is needed. As a starting point, we used 1H NMR for identifying gastric cancer biomarkers using a panel of gastric cancer spheroids and normal gastric spheroids. We were able to identify 8 chemical shift biomarkers for gastric cancer spheroids. Our data suggests that the cancerous and non-cancerous spheroids significantly differ in the lipid composition and energy metabolism. These results encourage the translation of these biomarkers into in-vivo gastric cancer detection methodology using MRI-MS.
语言:: eng
DOI:

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