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题目:: Cancer stem cell targeted therapy: progress amid controversies.
作者:: Wang(Tao),Shigdar(Sarah),Gantier(Michael P),Hou(Yingchun),Wang(Li),Li(Yong),Shamaileh(Hadi Al),Yin(Wang),Zhou(Shu-Feng),Zhao(Xinhan),Duan(Wei)
状态:: 发布时间2016-03-05 , 更新时间 2016-11-11
期刊:: Oncotarget
摘要:: Although cancer stem cells have been well characterized in numerous malignancies, the fundamental characteristics of this group of cells, however, have been challenged by some recent observations: cancer stem cells may not necessary to be rare within tumors; cancer stem cells and non-cancer stem cells may undergo reversible phenotypic changes; and the cancer stem cells phenotype can vary substantially between patients. Here the current status and progresses of cancer stem cells theory is illustrated and via providing a panoramic view of cancer therapy, we addressed the recent controversies regarding the feasibility of cancer stem cells targeted anti-cancer therapy.
语言:: eng
DOI:

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