| GeneLibs

题目:: Cancer-testis genes as candidates for immunotherapy in breast cancer.
作者:: Ghafouri-Fard(Soudeh),Shamsi(Roshanak),Seifi-Alan(Mahnaz),Javaheri(Mona),Tabarestani(Sanaz)
状态:: 发布时间2014-02-04 , 更新时间 2014-12-12
期刊:: Immunotherapy
摘要:: Cancer-testis (CT) antigens are tumor-associated antigens attracting immunologists for their possible application in the immunotherapy of cancer. Several clinical trials have assessed their therapeutic potentials in cancer patients. Breast cancers, especially triple-negative cancers are among those with significant expression of CT genes. Identification of CT genes with high expression in cancer patients is the prerequisite for any immunotherapeutic approach. CT genes have gained attention not only for immunotherapy of cancer patients, but also for immunoprevention in high-risk individuals. Many CT genes have proved to be immunogenic in breast cancer patients suggesting the basis for the development of polyvalent vaccines.
语言:: eng
DOI:: 10.2217/imt.13.165

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