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题目:: Chemokines in tumor progression and metastasis.
作者:: Sarvaiya(Purvaba J),Guo(Donna),Ulasov(Ilya),Gabikian(Patrik),Lesniak(Maciej S)
状态:: 发布时间2014-01-06 , 更新时间 2016-10-19
期刊:: Oncotarget
摘要:: Chemokines play a vital role in tumor progression and metastasis. Chemokines are involved in the growth of many cancers including breast cancer, ovarian cancer, pancreatic cancer, melanoma, lung cancer, gastric cancer, acute lymphoblastic leukemia, colon cancer, non-small lung cancer, non-hodgkin's lymphoma, etc. The expression of chemokines and their receptors is altered in many malignancies and leads to aberrant chemokine receptor signaling. This review focuses on the role of chemokines in key processes that facilitate tumor progression including proliferation, senescence, angiogenesis, epithelial mesenchymal transition, immune evasion and metastasis.
语言:: eng
DOI:: 10.18632/oncotarget.1426

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