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题目:: Cleft lip and palate in family members of cancer survivors.
作者:: Taioli(E),Ragin(C),Robertson(L),Linkov(F),Thurman(N E),Vieira(A R)
状态:: 发布时间2010-10-11 , 更新时间 2016-10-19
期刊:: Cancer Invest
摘要:: The presence of cleft lip with or without cleft palate (CL/P) in family members of cancer patients was investigated. An epidemiological questionnaire including family history of cancer and congenital oral cleft malformations was administered to 168 cancer survivors and a population-based sample of 170 healthy subjects. In the control group, 1.2% reported a family member with CL/P; among cancer survivors the figure was 4.2% (odds ratio: 3.7; 95% confidence interval: 0.75–17.8; p = .07). Among cancer survivors with a family member with CL/P, there was an apparent excess of testicular cancer and melanoma in comparison with the cancer survivors with no family history of CL/P. These preliminary results suggest a common etiologic background for cancer and CL/P.
语言:: eng
DOI:

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