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题目:: Is history of squamous-cell skin cancer a marker of poor prognosis in patients with cancer?
作者:: Askling(J),Sørensen(P),Ekbom(A),Frisch(M),Melbye(M),Glimelius(B),Hjalgrim(H)
状态:: 发布时间1999-10-27 , 更新时间 2006-11-15
期刊:: Ann Intern Med
摘要:: Nonmelanoma skin cancer is associated with increased occurrence of subsequent cancer and death from cancer, but it is not known whether a history of skin cancer is associated with poor prognosis after a second diagnosis of cancer.,To determine whether history of squamous-cell skin cancer is a marker of poor prognosis in patients with cancer.,Population-based cohort study.,Sweden, 1958 to 1996.,All patients in the Swedish Cancer Registry with or without a first diagnosis of squamous-cell skin cancer and a subsequent or first diagnosis of non-Hodgkin lymphoma (including chronic lymphocytic leukemia) or cancer of the colon, breast, prostate, or lung.,Relative risk (RR) for death determined by using Cox proportional hazards regression analysis.,Patients with a history of squamous-cell skin cancer had a significantly greater risk for death than those with no such history after receiving a diagnosis of non-Hodgkin lymphoma (RR, 1.33), colon cancer (RR, 1.24), breast cancer (RR, 1.19), or prostate cancer (RR, 1.17). Patients with lung cancer and a history of squamous-cell skin cancer who survived for 1 year after diagnosis of lung cancer also had an increased risk for death (RR, 1.29).,Patients with a registered history of squamous-cell skin cancer have a poor prognosis after diagnosis of subsequent cancer and warrant careful medical attention.
语言:: eng
DOI:

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