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题目:: Transcription profiling of Leishmania infantum, Leishmania major, Leishmania braziliensis intracellular amastigotes shows low level modulation between species and in different host genetic backgrounds
ID:
状态:: 发布时间April 1, 2009 , 更新时间 May 2, 2014 , 提交时间 Feb. 17, 2009,
物种:: Leishmania braziliensis, Leishmania infantum, Leishmania major
摘要:: Genome sequencing of species of the kinetoplastid parasite, Leishmania, that give rise to a range of disease phenotypes in the host has revealed highly conserved gene content and synteny across the genus. Only a small number of genes are differentially distributed between the three species studied to date, L. major, L. infantum and L. braziliensis. Here, we focus on RNA expression in the disease-promoting intracellular amastigotes and use customised oligonucleotide microarrays to confirm that all of these differentially-distributed genes are expressed in this critical stage of the parasite life cycle, with only a few regulated between species.
实验种类:: transcription profiling by array
样本量:: 7
实验设计:
: 无设计数据
数据号:: E-MEXP-2063
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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