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题目:: Transcription profiling from C. elegans ETC mutants vs. Wildtypes
ID:
状态:: 发布时间April 8, 2008 , 更新时间 June 10, 2011 , 提交时间 Dec. 14, 2007,
物种:: Caenorhabditis elegans
摘要:: Utilizing C. elegans as a model of mitochondrial dysfunction provides insight into cellular adaptations which occur as a consequence of genetic alterations causative of human disease. We characterized genome-wide expression profiles of hypomorphic C. ele; Our goal was to detect concordant changes among clusters of genes that comprise defined metabolic pathways utilizing gene set enrichment analysis. Experiment Overall Design: 3 biological replicates of each C. elegans strain were used as sources of total RNA combined for hybridization to a single Affymetrix whole-genome microarray. Comparison of the data was intended to reveal metabolic pathways downstream of the mutation.
实验种类:: transcription profiling by array
样本量:: 10
实验设计:
: 无设计数据
数据号:: E-GEOD-9897, GSE9897
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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