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题目:: Role of the AMP deaminase Amd1p in purines interconversion in Saccharomyces cerevisiae
ID:
状态:: 发布时间June 20, 2010 , 更新时间 May 2, 2014 , 提交时间 Nov. 8, 2007,
物种:: Saccharomyces cerevisiae
摘要:: In this work, we show that under specific conditions, defect in AMP deaminase activity strongly impairs yeast cell growth and we establish that AMP deaminase is required for correct balance between adenylic and guanylic nucleotides. Study of the Amd1p homologs, Yjl070p and Ybr284p, reveals that overexpression of these proteins cannot suppress phenotypes associated to /amd1/ deletion but instead mimic in a wild-type strain a loss of Amd1p function. Data presented combined global transcription analyses to measurements of intracellular nucleotides pools by HPLC. Keywords: yeast strains implied in purines interconversion. 4 biological samples in dye-swap.
实验种类:: transcription profiling by array
样本量:: 12
实验设计:
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数据号:: E-GEOD-9557, GSE9557
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