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题目:: 300 ppm Citrinin treatment for 2 h (GPL1945)
ID:
状态:: 发布时间June 10, 2010 , 更新时间 May 2, 2014 , 提交时间 Oct. 22, 2006,
物种:: Saccharomyces cerevisiae
摘要:: The availability of yeast DNA microarrays provides the possibility of monitoring gene expression levels as a function to toxin exposure, and consequently as a means of determining mechanisms of toxicity. This system possesses the benefit of the essential volume of yeast cultures, the high reproducibility of expression profiles, and the massive functional information. Because small amount of biological sample cultures are required for this analysis, toxicity test for rare chemical such as mycotoxins which is a natural compound and difficult to be artificially synthesized. Citrinin [518-75-2], 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-crboxylic acid, is the one of the popular mycotoxicin produced by Penicillium and Aspergillus family possibly spread all over the world. This natural chemicals is one of the well characterized mycotoxin but the information especially mechanism of toxic action is limited. We used two types of microarrays, one have ORF (Open reading Frame) fragment on the surface of the glass as probes and the other have probes as oligonucleotide probes on the microarray with 3 dimensions. We compared data properties and studied the toxicity of citrinin to yeast cells. Keywords: stress response Series containes 3 hybridization results from independent biological samples, and each experiment have high and low power scanned data respectively.
实验种类:: unknown experiment type
样本量:: 12
实验设计:
: 无设计数据
数据号:: E-GEOD-6111, GSE6111
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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