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题目:: Physical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays
ID:
状态:: 发布时间Sept. 9, 2005 , 更新时间 March 27, 2012 , 提交时间 Sept. 7, 2005,
物种:: Homo sapiens
摘要:: Somatic cell mutants can be informative in the analysis of a wide variety of cellular processes. The use of map- based positional cloning strategies in somatic cell hybrids to analyze genes responsible for recessive mutant phenotypes is often tedious, however, and remains a major obstacle in somatic cell genetics. To fulfill the need for more efficient gene mapping in somatic cell mutants, we have developed a new DNA microarray comparative genomic hybridization (array-CGH) method that can rapidly and efficiently map the physical location of genes complementing somatic cell mutants to a small candidate genomic region. Here we report experiments that establish the validity and efficacy of the methodology. Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Using regression correlation
实验种类:: unknown experiment type
样本量:: 4
实验设计:
: 无设计数据
数据号:: E-GEOD-3269, GSE3269
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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