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题目:: Genome wide transcriptome profiling of a murine acute melioidosis model reveals new insights into how Burkholderia pseudomallei overcome host innate immunity
ID:
状态:: 发布时间Dec. 23, 2010 , 更新时间 March 27, 2012
物种:: Mus musculus
摘要:: The purpose of this study was to develop a comprehensive picture of the host transcriptional response during the acute stage of melioidosis. To adress this, we compared the transcriptome of infected liver and spleen with uninfected tissues over an infection period of 42 hr (16 hpi, 24 hpi and 42 hpi, respectively) to identify genes whose expression is altered in response to an acute infection. The microarray experimental design included 3 biological replicates for each time point and both liver and spleen were harvested for RNA extraction (except the liver 0 hpi only has 2 biological replicates). The microarray data from each time point was compared relative to uninfected mice.
实验种类:: transcription profiling by array
样本量:: 23
实验设计:
: 无设计数据
数据号:: E-GEOD-25074, GSE25074
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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