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题目:: Neonatal beta cells lack the specialized metabolic phenotype of mature beta cells
ID:
状态:: 发布时间Feb. 22, 2011 , 更新时间 May 3, 2014
物种:: Rattus norvegicus
摘要:: Fetal and neonatal beta cells have poor glucose-induced insulin secretion and only gain robust glucose responsiveness several weeks after birth. This unresponsiveness may be due to a generalized immaturity of the metabolic pathways normally found in beta cells. Gene expression profile of neonatal (1 day old) and young adult (6 weeks old) Sprague-Dawley rat islets were evaluated and compared. Frozen sections were obtained from pancreases of neonatal (1 day old) and young adult (6 weeks old) Sprague-Dawley rats. The beta cell enriched cores of the islets were excised using laser capture microdissection. RNA was extracted, amplified and subjected to microarray analysis.
实验种类:: transcription profiling by array
样本量:: 7
实验设计:
: 无设计数据
数据号:: E-GEOD-24790, GSE24790
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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