Specification of functional floor plate tissue from human embryonic stem cells occurs at the expense of anterior neurectoderm
ID:
状态:
发布时间April 12, 2010
, 更新时间 March 27, 2012
, 提交时间 March 1, 2010,
物种:
Homo sapiens
摘要:
Here we report the derivation of human embryonic stem cells (hESC-) derived FP tissue capable of secreting Netrin-1 and SHH and patterning primary and hESC derived tissues. Three replicate plates of human embryonic stem cells (A-C) were differentiated to various days (D#) using Noggin+SB431542 with or without SHH (C25II)