| GeneLibs

题目:: Transcription profiling of human drug-resistant Panc1/mock cells and Panc1 cells expressing wildtype syk
ID:
状态:: 发布时间Sept. 18, 2009 , 更新时间 June 10, 2011 , 提交时间 Sept. 8, 2009,
物种:: Homo sapiens
摘要:: We recently identified the nonreceptor tyrosine kinase syk as a tumor suppressor in pancreatic ductal adenocarcinoma cells. Reintroduction of syk into Panc1 cells promoted a more differentiated phenotype and retarded invasion and tumorigenic growth. Gene array analysis identified over 2,000 transcripts differentially expressed at FDR<0.01. Among these were members of the MMP2 axis, which were subsequently shown to regulate Panc1 invasion. Experiment Overall Design: Affymetrix global gene arrays were used to analyse differences in gene expression patterns in Panc1 cells stably reexpressing syk, or vector-only mock controls. RNA was harvested from cells grown under identical conditions in standard culture.
实验种类:: transcription profiling by array
样本量:: 2
实验设计:
: 无设计数据
数据号:: E-GEOD-18000, GSE18000
数据状态:: 无法自动分析，您可以尝试手动分析数据。

实验库数据相关信息