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题目:: Comparative Genome Hybridization Reveals Few Genetic Differences between Aspergillus flavus and A. oryzae
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状态:: 发布时间April 10, 2010 , 更新时间 June 10, 2011
物种:: Aspergillus flavus, Aspergillus oryzae
摘要:: Aspergillus flavus and A. oryzae represent two unique species predicted to have spent centuries in vastly different environments. A. flavus is an important opportunistic plant pathogen known for contaminating crops with the carcinogenic mycotoxin, aflatoxin and A. oryzae is a domesticated fungus used in food fermentations. Remarkably, the genomes of these two species are still nearly identical. We have used the recently sequenced genomes of A. oryzae RIB40 and A. flavus NRRL3357 along with array based comparative genome hybridization (CGH) as a tool to compare genomes across several strains of these two species. A comparison of three strains from each species by CGH revealed only 42 and 129 genes unique to A. flavus and A. oryzae, respectively. Further, only 709 genes were identified as being polymorphic between the species. Despite the high degree of similarity between these two species, correlation analysis among all data from the CGH arrays for all strains used in this study reveals a species split. However, this view of species demarcation becomes muddled when focused on only those genes for secondary metabolism. CGH comparison between 3 strains of A. flavus and 3 strains of A. oryzae, analyzed at the probe level
实验种类:: comparative genomic hybridization by array
样本量:: 6
实验设计:
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数据号:: E-GEOD-15650, GSE15650
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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