| GeneLibs

题目:: Transcription profiling of mouse normal lymphoid progenitors and MLL-AF4 leukemic lymphoblasts
ID:
状态:: 发布时间Nov. 13, 2008 , 更新时间 March 27, 2012 , 提交时间 July 31, 2008,
物种:: Mus musculus
摘要:: We created a mouse model where conditional expression of physiologic levels of an Mll-AF4 fusion oncogene induces development of acute lymphoblastic (ALL) or acute myeloid leukemias (AML). Immunophenotypic and gene expression analysis of the ALL cells demonstrated bone marrow replacement with B-precursor cells which express a gene expression profile that has significant overlap with profiles in human MLL-rearranged ALL. Experiment Overall Design: Total RNA from normal pro-B, pre-B, immature B and mature B lymphocytes, and from leukemic pre-B cells was isolated and hybridized to Affymetrix expresison microarrays.
实验种类:: transcription profiling by array
样本量:: 39
实验设计:
: 无设计数据
数据号:: E-GEOD-12310, GSE12310
数据状态:: 无法自动分析，您可以尝试手动分析数据。

实验库数据相关信息