| GeneLibs

题目:: Transcription profiling of mouse dermal fibroblasts to identify interleukin-1-induced gene expression
ID:
状态:: 发布时间Jan. 14, 2009 , 更新时间 May 3, 2014 , 提交时间 July 29, 2008,
物种:: Mus musculus
摘要:: Interleukin-1 (IL-1) is produced from immune-activated cells upon infection and tissue injury, and stimulates a variety of cells expressing its receptor. IL-1 receptor activation results in intracellular signaling cascades that culminate in the activation of transcription factors such as NF-kappaB, AP-1, and C/EBPbeta. To identify genes whose expression is induced in response to IL-1, we performed DNA microarray analysis of IL-1-treated murine dermal fibroblasts (DFs). The gene expression patterns in control, untreated DFs and in DFs treated with IL-1 were compared. Experiment Overall Design: Total RNAs from untreated DFs (0 h) vs. IL-1-treated DFs (1 h, 2 h, or 4 h after IL-1 treatment) were isolated and analyzed using an Agilent DNA microarray platform. Hybridization was performed in duplicate for dye swapping.
实验种类:: transcription profiling by array
样本量:: 12
实验设计:
: 无设计数据
数据号:: E-GEOD-12285, GSE12285
数据状态:: 无法自动分析，您可以尝试手动分析数据。

实验库数据相关信息