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题目:: Transcription profiling of human Mesenchymal Stem Cells (MSC) vs reference RNA of non-multipotent human fibroblasts HS68
ID:
状态:: 发布时间Aug. 23, 2005 , 更新时间 May 1, 2014 , 提交时间 Nov. 16, 2004,
物种:: Homo sapiens
摘要:: Mesenchymal stem cells (MSC) resemble a multipotent adult stem cell population capable of differentiation into a number of different mesodermal cell types including adipodytes, osteoblasts, chondroblasts. Although still in debate there is some evidence, that these cells can also differentiate into cells of non-mesodermal germal layers including hepatocytes, myocytes, cardiomyocytes or neurons. Analysis of these cells in the course of differentiation makes them an intriguing model for the examination of stemness. More importantly the differentiation capacity of MSC raises high hopes for clinical applications. In this study we have isolated MSC from bone marrow under two different culture conditions, from adipose tissue and from umbilical cord blood. The genome wide gene expression profile of these different human MSC was compared with reference RNA of non-multipotent human fibroblasts HS68. The aim of this study was to elucidate common molecular characteristics of MSC as well as differences in their expression profile. These results might help for a better understanding of MSC and contribute to a reliable quality control that will be necessary for clinical applications.
实验种类:: transcription profiling by array
样本量:: 20
实验设计:
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数据号:: E-EMBL-4
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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